Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
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Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor Descriptor: 4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1H)-yl]methyl}phenyl)amino]-4-oxobutanoic acid, Mitogen-activated protein kinase 10 Authors: Sogabe, S, Ohra, T, Itoh, F, Habuka, N, Fujishima, A. Deposit date: 2007-11-27 Release date: 2008-09-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1) Bioorg.Med.Chem., 16, 2008
创建时间:
2007-11-27



