Haplotype analysis of the FOXE1 locus in Spanish classic Papillary Thyroid Carcinoma cases versus controls.

aHaplotype frequencies were estimated using the PHASE program with 10,000 permutations.bThe LD region studied spans from coordinates 99,648,503 to 99,668,059 on chromosome 9 for a total length of 19.5 kb.cHaplotype risks were calculated using the Haplo.Stats package in R, considering the overrepresented haplotype in controls (haplotype #1) as the reference.Significant risk.conferring haplotype (haplotype #2) is highlighted in bold case.PTC, Papillary Thyroid Carcinoma; OR, Odds Ratio.