Cenobamate exhibits prophylactic and therapeutic efficacy against cisplatin-induced peripheral neuropathy in rats: Behavioral and mechanistic insights

This dataset contains raw behavioral and immunohistochemical data supporting the study titled "Cenobamate exhibits prophylactic and therapeutic efficacy against cisplatin-induced peripheral neuropathy in rats: Behavioral and mechanistic insights."
Behavioral data include measurements of pain sensitivity and motor function obtained from rat models of cisplatin-induced peripheral neuropathy (CIPN). Sensory assessments include mechanical allodynia (dynamic plantar aesthesiometer), cold allodynia (acetone drop test), and thermal hyperalgesia (Hargreaves test). Motor function assessments include rotarod performance and footprint gait analysis.
Immunohistochemical data include quantitative H-score measurements for brain-derived neurotrophic factor (BDNF), cleaved caspase-3, and interleukin-1β (IL-1β) in dorsal root ganglia (DRG) and sciatic nerve (SN) tissues.
The dataset includes Excel files containing raw measurements and processed values used for statistical analysis. Data correspond to both prophylactic and therapeutic experimental protocols evaluating cenobamate effects compared with cisplatin and gabapentin-treated groups.