Expression data from SHP specific siRNA or nonspecefic siRNA transfected rat astrocytes [extended study]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE82247
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资源简介：
To clarify the effect of SHP in LXRs-mediated signaling pathway, we performed global gene expression analysis of SHP siRNA transfected- or control siRNA transfected- astrocytes after IFN-γ and LXRs agonist. Microarray analysis revealed that expression of several genes encoding inflammatory mediators were reversed in SHP siRNA transfected-astrocytes, when compared with control siRNA transfected-astrocytes. Primary astrocytes were cultured from the cerebral cortices of 1 day-old Sprague-Dawley rats. The astrocytes transfect with control siRNA or SHP siRNA and treated withIFN-γ in the presence or absence of GW for 3 h. This study includes a re-analysis of GSM2036031, GSM2036032, GSM2036033, and GSM2036034 from GSE76704.
创建时间：
2019-02-07
