Crystal structure of FGFR2 kinase domain gatekeeper mutant V564F in complex with covalent compound 19
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Crystal structure of FGFR2 kinase domain gatekeeper mutant V564F in complex with covalent compound 19 Descriptor: 1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-one, CITRATE ANION, Fibroblast growth factor receptor 2, ... Authors: Ke, J, Wibowo, A.S, Carter, J.J, Larsen, N.A. Deposit date: 2020-10-23 Release date: 2021-02-10 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3. Acs Med.Chem.Lett., 12, 2021
创建时间：
2020-10-23
