five

The structure of co-crystals of 8r-B-EGFR WT complex

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Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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The structure of co-crystals of 8r-B-EGFR WT complex Descriptor: 6-(2-chloranyl-3-fluoranyl-phenyl)-5-methyl-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[(3S)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one, Epidermal growth factor receptor Authors: Zhu, S.J, Yun, C.H. Deposit date: 2019-04-04 Release date: 2020-04-15 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.796 Å) Cite: Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S). J.Med.Chem., 62, 2019
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2019-04-04
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