Additional file 8: of Exome scale map of genetic alterations promoting metastasis in colorectal cancer

Table S7. EMV Cancer driver mutations according to CHASM algorithm. Chrom – chromosome number, Position – mutation position, Ref – reference base, Alt – variant base, Sample.ID – sample with mutation, HUGO.symbol – HUGO gene symbol, Protein.sequence.change – amino-acid change. CHASM.p.value – p-value for CHASM, dbSNP – identifier in dbSNP, 1000.Genomes/ ESP6500/ ExAC – allele frequencies in different exome-sequencing projects, COSMIC.ID – COSMIC identifier, Occurrences.in.COSMIC.by .primary.sites – organs, harboring somatic mutations in this gene in COSMIC database, ClinVar.Clinical.Significance – ClinVar clinical significance, Number.of.samples – number of samples with mutation, Qvalue – CHASM.p.value corrected for multiple testing with FDR method (XLSX 291 kb)