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Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). This structure has been obtained from crystals soaked for 6 hours.

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). This structure has been obtained from crystals soaked for 6 hours. Descriptor: (2S)-2-(4-{2-[1,3-BENZOXAZOL-2-YL(HEPTYL)AMINO]ETHYL}PHENOXY)-2-METHYLBUTANOIC ACID, Peroxisome proliferator-activated receptor gamma Authors: Pochetti, G, Mazza, F. Deposit date: 2006-08-23 Release date: 2007-04-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands J.Biol.Chem., 282, 2007
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2006-08-23
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