Tissue hydration and collagen parameters measured before (CXL-) and after (CXL+) riboflavin/UVA collagen cross-linking.

Average values (+/− SEM) of collagen parameters for all samples (excluding N10–N15) were calculated using >50 measurements recorded from the central 8 mm region of the same corneas before (CXL−) and after cross-linking (CXL+). Averaged data shown for samples N10–N15 (3 pairs of corneas in which the left of each pair (N10, N12 and N14) was cross-linked (CXL+) and the right (N11, N13 and N15) remained untreated (CXL−)) is based on a single measurements obtained from the centre of each cornea. Bold type is used to indicate pre and post treatment differences in collagen parameters at p