Myofibroblast-specific 5-HT2B Mediates Adverse Remodeling Following Myocardial Infarction
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介：
We report that ablation of the serotonin 2B receptor in periostin-expressing cells improves cardiac structure and function following myocardial infarction. We isolated PDGFRa expressing cells during the fibrotic healing phase after injury, and show that these cells have alterations in the expression of genes controlling cell cycle progression as well as a few markers of cell adhesion and migration.
提供机构：
Vanderbilt University
创建时间：
2022-02-20
