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Colocalization of PrP<sup>Sc</sup> and olfactory marker protein in olfactory receptor neurons.

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aThe individual regions of olfactory receptor neurons (ORN) was determined following anti-OMP immunofluorescence and confocal images were cropped to each region of interest prior to deconvolution and co-localization analysis as described in the materials and methods. bAverage Overlap Coefficient after Manders ± SEM, N = 27. cColocalization coefficient M2 indicates the percentage of PrPSc that overlaps with OMP in the region of analysis. *p-value<0.0001, comparison between mock and HY TME infected tissues using Welch's two-sample t-test.

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2010-04-15
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