CRISPR screen to identify regulators of neuronal differentiation
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CRISPR screen to identify regulators of neuronal differentiation
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2024-01-12
相关数据集
Sequencing data from CRISPR screen
Sequencing data from the following publication:Wu, J.L.Y., Ji, Q., Blackadar, C. et al. The pathways for nanoparticle transport across tumour endothelium. Nat. Nanotechnol. (2025). https
DataCite Commons2025-03-17 更新40
Manipulating the transcriptome and chromatin accessibility in T cells through CRISPR-induced alternative splicing of IKZF1 (ATACseq)
Genome-wide association studies have identified statistically significant associations between genetic variants in or near the IKZF1 gene and several autoimmune disorders. IKZF1, encoding the transcri
NIAID Data Ecosystem30
Genome-scale CRISPR-Cas9 screen of OVCAR3 and CCL218 cancer cells with or without hydroxychloroquine
A Brunello CRISPR-Cas9 library screen was performed with OVCAR3 and CCL218 cells in the presence or absence of hydroxychloroquine. Drug pulse chases were used, with 48h of drug exposure followed by re
NIAID Data Ecosystem00
The Ubiquitin Ligase Praja1 Reduces NRAGE Expression and Inhibits Neuronal Differentiation of PC12 Cells
Evidence suggests that regulated ubiquitination of proteins plays a critical role in the development and plasticity of the central nervous system. We have previously identified the ubiquitin ligase Pr
Figshare2016-01-18 更新40
Differential gene expression (FDR 0.05) for CRISPR edited clones.
hTLR4 Cells were transfected a CRISPR/Cas9 construct and a gRNA specific for the rs17622517 locus. Wild type, heterozygous or homozygous clones were isolated and then treated with no LPS, LPS for 90 m
Figshare2021-07-27 更新00
