Putative gene candidates with phylogenetic support for HGT.

1Two similar proteins annotated as hypoxanthine phosphoribosyltranferase are observed in M. haemofelis and M. haemocanis (MHF_0096, 0098 and MHC_00425, 00435; 24–26% identity, 475 to 498 amino acids long). It is possible that MHF_0096 and MHC_00425 are the Mollicutes-related genes and were not horizontally transferred; while MHF_0098 and MHC_00435, homologs to WEN_00280, were horizontally acquired, as demonstrated for WEN_00280.2Three copies of this gene were observed in M. haemofelis (Ohio2 and Langford1) and 4 copies were observed in M. haemocanis; only the genes listed were associated with HGT.3There are two copies of this gene in M. haemofelis and M. haemocanis; therefore, there is possibility of gene duplication and the results should be evaluated with caution.