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Impact of COP1 silencing on hepatoma and hepatocyte transcriptomics

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206116
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Transfection experiments aimed at understanding the role of COP1 in hepatocytes and hepatoma models HuH-7 cells, HepG2 cells (hepatocyte-derived carcinoma cell line) or a lot of commercial primary hepatocytes (HMCPMS) from ThermoFisher Scientific were transfected for 96 h with 10 nM siRNA targeting either a RFWD2/COP1 or a control (NT1) siRNA. RNA was then harvested and the transcriptome analyzed by transcription array. Each file corresponds to a distinct biologic: the experiment was repeated on 2 -3 distinct occasions.
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2025-03-11
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