CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor
收藏Protein Data Bank Japan2025-04-09 更新2026-03-21 收录
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https://pdbj.org/mine/summary/1h01
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CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor Descriptor: (2R)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, CYCLIN-DEPENDENT KINASE 2, ... Authors: Breault, G.A, Ellston, R.P.A, Green, S, James, S.R, Jewsbury, P.J, Midgley, C.J, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E. Deposit date: 2002-06-10 Release date: 2003-07-11 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines Bioorg.Med.Chem.Lett., 13, 2003
创建时间：
2002-06-10
