Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol

Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. Deposit date: 2021-10-26 Release date: 2022-03-09 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (2.74 Å) Cite: Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022添加胆固醇的去配基态电鳐乙酰胆碱受体冷冻电镜（Cryo-EM）结构 描述物：(2S)-3-(十六酰氧基)-2-[(9Z)-十八碳-9-烯酰氧基]丙基 2-(三甲基铵)乙基磷酸酯、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖…… 作者：Rahman, M.M、Basta, T、Teng, J、Lee, M、Worrell, B.T、Stowell, M.H.B、Hibbs, R.E. 存档日期：2021-10-26 发布日期：2022-03-09 最后修改日期：2025-05-28 实验方法：电子显微镜（分辨率2.74埃） 引用文献：肌肉型烟碱乙酰胆碱受体脱敏及筒箭毒碱阻断的结构机制。《自然·结构与分子生物学》（Nat.Struct.Mol.Biol.），第29卷，2022年