De novo assembly and annotation of parasitic trematode genomes

Contained in this release are 19 genome assemblies and annotations of parasitic trematodes, encompassing 13 species. This included representatives of the <em>Schistosoma</em> (<em>n</em> = 13 assemblies), <em>Trichobilharzia</em> (<em>n</em> = 2 assemblies), <em>Heterobilharzia americana</em> (<em>n</em> = 2 assemblies) and <em>Dicrocoelium dendriticum </em>(<em>n </em>= 1 assembly). The <em>Schistosoma curassoni</em> assembly has been released previously (10.5281/zenodo.6594833) but a new annotation is included with the original assembly here. These genomes were assembled from a variety of sources including stored parasites from museum collections, established laboratory strains and wild-caught isolates sampled from natural hosts in endemic regions. Using a combination of DNA sequencing approaches, all genomes were assembled into chromosomal-scale scaffolds. This was followed by genome annotation based on short-read RNA sequencing (RNA-seq) and long-read isoform sequencing (Iso-seq) transcriptomic data. Included here are the primary assemblies (representing a non-redundant haploid genome) for each species (*.primary.fa), alternate loci (alternate representations of loci found in a largely haploid assembly; *.haplotypes.fa) and annotations (*.gff3). Metadata for each assembly can be found in the included spreadsheets (metadata.xlsx). This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see https://www.sanger.ac.uk/about/research-policies/open-access-science/. This repository will be updated with a complete list of collaborators/authors prior to publication. Please contact Duncan Berger ([e-mail]) with questions regarding pre-publication use of this dataset.