The overall goal of this project is to identify transcriptome alteration in fetal islets exposed to transient maternal hyperglycemia from GD20 to GD22. Overall design: Left uterine horn fetus rats wer

NIAID Data Ecosystem70

Transcriptomic profiling of alpha, beta, and delta cell populations provides new insights into the role of ghrelin in the pancreas

胰腺转录组学

ghrelin信号通路

Intra-islet crosstalk between islet cells is critical in orchestrating the bodyâs response to changes in blood glucose levels, but is incompletely understood. In this study, we used transgenic mouse

NIAID Data Ecosystem60

RNA-Seq analysis of porcine islets and pancreas to characterize the differentially expressed genes between higher and lower islet density

胰腺转录组学

差异基因表达分析

Gene expression patterns that form the basis for the observed variation in islet density among porcine pancreata were examined. RNA-Seq analysis was performed to investigate differential gene expressi

NIAID Data Ecosystem70

RNAseq analysis of 8week old islets from murine Abca12 KO pancreas. RNAseq analysis of 8week old islets from murine Abca12 KO pancreas

胰腺转录组学

基因敲除功能研究

The goal of this study was to identify changes in the transcriptome that occur following Abca12 gene deletion relative to Control islets Overall design: Islets were isolated from 8 week old mice from

NIAID Data Ecosystem60

RNA-Seq of pancreatic islets derived from mice fed a long-term high-fat diet against chow-fed controls

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