Timeliness of referral policies in target domain.

There were 307 and 158 patients died or received LTx during 2015 and 2017 in the considered UK and Canadian CF cohorts, respectively. A timely referral policy shall suggest LTx referral for these patients based on the annual follow-up information in 2014. The referral result of the baselines and AutoPrognosis model developed on the source data (UK cohort) were evaluated on such subgroup of CF patients. For each policy applied to this subgroup, patients predicted as low-risk were counted under the column of delayed. Patients predicted to be high-risk were counted in the column of timely. The numbers were reported with 95% CI via models obtained from stratified ten-fold cross-validation on the UK CF dataset.