Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine
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Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine Descriptor: N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine, SULFATE ION, Vascular endothelial growth factor receptor 2 Authors: Nolte, R.T. Deposit date: 2008-03-12 Release date: 2008-10-07 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J.Med.Chem., 51, 2008
创建时间：
2008-03-12
