IL20
收藏rgd.mcw.edu2025-03-26 收录
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资源简介：
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]
该基因编码的蛋白质是一种与白介素10（IL10）结构上相关的细胞因子。研究表明，该细胞因子可通过信号转导和转录激活因子3（STAT3）在角质细胞中传递其信号。在皮肤中发现了针对该细胞因子的特定受体，且在银屑病皮肤中显著上调，这表明该蛋白在表皮功能和银屑病中发挥重要作用。[资料来源：RefSeq，2008年7月]
提供机构：
Rat Genome Database
