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Contemporary survival of patients with pulmonary arterial hypertension and congenital systemic to pulmonary shunts

Global Health Data Exchange ()2024-06-26 收录

肺动脉高压

疾病生存分析

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资源简介：

Contemporary survival of patients with pulmonary arterial hypertension and congenital systemic to pulmonary shunts

应用场景：

肺动脉高压

衰老细胞清除

To explore the role played by senescent cells in mice models of pulmonary hypertension we exposed young C57BL6/j mice to 8 days hypoxia or normoxia and treated with senolytic drug ABT-263 (50mg/kg/day

NIAID Data Ecosystem90

Verification of the hypoxia-induced PAH model in rats in this study.

肺动脉高压

低氧生理实验

Norm: normal group n = 10, Hypo: Hypoxia group n = 10; RVSP: Right ventricular systolic pressure, mPAP mean pulmonary artery pressure, RV/(LV+S): right ventricle to left ventricle plus septum. Table 1

NIAID Data Ecosystem30

Echocardiographic signs suggesting PAH used to assess the probability of PAH in addition to tricuspid regurgitation velocity measurement in Table 3 [21].

超声心动图诊断

肺动脉高压

Echocardiographic signs suggesting PAH used to assess the probability of PAH in addition to tricuspid regurgitation velocity measurement in Table 3 [21].

NIAID Data Ecosystem20

Fcer1a全身敲除并建立低氧诱导小鼠肺动脉高压模型实验数据集

肺动脉高压

免疫学

全身敲除Fcer1a后建立低氧诱导肺动脉高压模型，对照组小鼠为WT小鼠。低氧建模4周后在体进行心动超声检测，测量小鼠肺动脉血流多普勒。随后取材检测小鼠RVSP，RVHI，病理衡量小鼠肺血管厚度和肌化程度。实验结果显示敲除IgE受体Fcer1a可以缓解低氧所致肺动脉高压和肺血管重塑。

国家人口健康科学数据中心30

Correlations with clinical parameters (Spearman r and p-value) for n = 24 patients.

肺动脉高压

肺功能参数

mPAP: mean pulmonary arterial pressure, PVR: pulmonary vascular resistance, AVDO2: arterial-venous difference in oxygen content, art SO2: arterial oxygen saturation, ven SO2: venous oxygen saturation,

NIAID Data Ecosystem20

Contemporary survival of patients with pulmonary arterial hypertension and congenital systemic to pulmonary shunts

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