Validation of the histotype of commonly used ovarian carcinoma cell lines using immunohistochemistry based prediction via COSP and mutational profiling.

COSP and AIRD1A markers were scored as positive (1) or negative (0), except for p53: null mutation (0), wildtype (1), mutated (2).ARID1A IHC: a – corresponding ARID1A nonsense or frameshift mutation detected, b – no ARID1A mutation detected in sequencing data (if no letter code, sequence information was unavailable)COSP algorithm can be found at http://www.gpec.ubc.ca/index.php?content=papers/ovcasubtype.phpTP53 mutations are noted as heterozygous (het) or Homozygous/Hemizygous (Hm)*Sequencing of BRAF, KRAS, ERBB2, NRAS, CTNNB1, EGFR, PTEN, PIK3CA, PPP2R1A, DICER1 and ARID1A