Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM and allosteric inhibitor compound 35
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/7kdb
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM and allosteric inhibitor compound 35 Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-(4-hydroxyphenyl)-2,3-diphenyl-5-[(1H-pyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-7(4H)-one, ... Authors: Padyana, A, Jin, L. Deposit date: 2020-10-08 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion. J.Med.Chem., 64, 2021
创建时间：
2020-10-08
