Additional file 1: of Conserved regulation of RNA processing in somatic cell reprogramming

Gene set enrichment analysis of SRP016568. The file contains an XLSX spreadsheet summarizing the top 20 most enriched gene ontology (GO) terms among the 6278 genes that were significantly more highly expressed in iPSCs compared to foreskin fibroblasts in the study [21]. For comparison, the statistics for the same GO terms are also shown for the gene set enrichment analysis done using all 11705 differentially expressed genes. A total of 17249 genes were found to be expressed in the data sets and were used as background. The first four columns, from left to right, indicate the GO term identifier, name, ontology class/namespace, and the total number of (human) genes that are associated with the term. The next three columns indicate the number of genes associated with the term that were found more highly expressed in iPSCs, the false discovery rate (FDR; Benjamini-Hochberg) and the rank (by FDR) for the GO term enrichment. The remaining three columns indicate the same parameters for all differentially expressed genes. RNA-related GO terms have their names and identifiers in bold and italics. Asterisks next to GO term identifiers indicate that the term has the exact same set of genes associated with it as the preceding one and is thus redundant. (XLSX 6 kb)