As pharmaceutical excipients, mesoporous silica nanoparticles (MSNs) have attracted considerable concern based on potential risks to the public. The impact of MSNs on biochemical metabolism is poorly
Purpose: The purpose of this study was to compare the hepatic transcriptome in the control group and severe acute pancreatitis, in order to identify metabolic gene changes during pancreatitis. Methods
wy-14643 activates PPARA to promote beta oxidation. SIRT6 is known to promote beta oxidation. Here we examine the effect of PPARA activation in SIRT6 heterozygote mice. Overall design: Liver mRNA prof
