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Ternary complex structure of Cereblon-DDB1 bound to IKZF2(ZF2) and the molecular glue DKY709

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Protein Data Bank Japan2023-10-25 更新2026-03-28 收录
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Ternary complex structure of Cereblon-DDB1 bound to IKZF2(ZF2) and the molecular glue DKY709 Descriptor: (3S)-3-[5-(1-benzylpiperidin-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA damage-binding protein 1, ... Authors: Ma, X, Ornelas, E, Clifton, M.C. Deposit date: 2022-03-08 Release date: 2023-03-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy. Cell Chem Biol, 30, 2023
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2022-03-08
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