Increasing evidence has shown that the metabolism and clearance of molecular targeted agents, such as sorafenib, plays an important role in mediating the resistance of HCC cells to these agents. Metab

NIAID Data Ecosystem20

Table_1_Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.xls

肝细胞癌药物敏感性

铁死亡机制

PurposeRecently, long noncoding RNA LINC01134 has been shown to reduce cell viability and apoptosis via the antioxidant stress pathway, thereby enhancing OXA resistance in hepatocellular carcinoma. Ho

NIAID Data Ecosystem10

Table 6_β-caryophyllene sensitizes hepatocellular carcinoma cells to chemotherapeutics and inhibits cell malignancy through targeting MAPK signaling pathway.xlsx

肝细胞癌药物敏感性

MAPK靶向治疗

Backgroundβ-caryophyllene (BCP) is a naturally occurring bicyclic sesquiterpene extracted from various plants, and widely used as a medicinal agent for various diseases. During hepatocellular carcinom

NIAID Data Ecosystem20

Table 1_Manganese modulates hepatocellular carcinoma cytotoxicity and doxorubicin sensitivity in a dose dependent manner.xlsx

肝细胞癌药物敏感性

锰剂量依赖性调控

IntroductionHepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality globally, characterized by decreased manganese (Mn) levels in tumor tissues compared to noncancerous liver tis

NIAID Data Ecosystem10

Additional file 10 of Corynoline enhances sorafenib sensitivity in hepatocellular carcinoma via NOS3-mediated ROS production

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