Abcg2

ENCODES a protein that exhibits ABC-type xenobiotic transporter activity (ortholog); amide transmembrane transporter activity (ortholog); ATPase-coupled transmembrane transporter activity (ortholog); INVOLVED IN biotin transport (ortholog); cellular detoxification (ortholog); cellular response to dexamethasone stimulus (ortholog); PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; erlotinib pharmacodynamics pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute megakaryocytic leukemia (ortholog); acute myeloid leukemia (ortholog); FOUND IN apical plasma membrane (ortholog); brush border membrane (ortholog); external side of apical plasma membrane (ortholog)

编码一种呈现ABC型外来物转运蛋白活性（同源物）；酰胺跨膜转运蛋白活性（同源物）；ATP酶偶联跨膜转运蛋白活性（同源物）；参与生物素转运（同源物）；细胞解毒（同源物）；细胞对地塞米松刺激的反应（同源物）；参与多西他赛药代动力学途径；阿霉素药代动力学途径；厄洛替尼药代动力学途径；与急性淋巴细胞白血病（同源物）、急性巨核细胞白血病（同源物）、急性髓系白血病（同源物）相关；位于细胞顶端质膜（同源物）、刷状缘膜（同源物）、细胞顶端质膜外侧（同源物）