Genome of the isolates: Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities

The draft genome of the isolates in Mouse Intestinal Bacteria Collection (miBC)

Microbiome research is hampered by the fact that many bacteria are still unknown and by the lack of publicly available isolates. Fundamental and clinical research is in need of comprehensive and well-curated repositories of cultured bacteria from the intestine of mammalian hosts. Due to host-specific features of the gut microbiota, it is sound to establish collections of isolates from single host species. Hence, this project established a collection of bacterial strains isolated from the intestine of mice.

The original version of the collection published in 2016 (Lagkouvardos, et. al. 2016. Nat. Microbiol.). was doubled by the addition of 112 strains, representing a total of 141 species across 6 phyla and 35 families for the entire collection. As we aimed to create a well-curated resource, all bacterial species within miBC have been taxonomically described and are publicly available.