HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor
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HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor Descriptor: HIV-1 PROTEASE, N,N-[2,5-O-DI-3-FLUORO-BENZYL-GLUCARYL]-DI-[1-AMINO-INDAN-2-OL] Authors: Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T. Deposit date: 2004-08-10 Release date: 2004-12-01 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy Eur.J.Biochem., 271, 2004
创建时间:
2004-08-10



