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Regulation of pluripotency and self-renewal of ES cells through epigenetic-threshold modulation and mRNA pruning

ChEBI2012-10-26 更新2026-07-21 收录

细胞表观遗传调控

多能性维持机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-39513 数据链接链接失效反馈

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Regulation of pluripotency and self-renewal of ES cells through epigenetic-threshold modulation and mRNA pruning

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创建时间：

2012-10-26

细胞表观遗传调控

组蛋白甲基化功能

Germ cells have evolved unique mechanisms to ensure an everlasting transmission of their genetic and epigenetic information to future generations, whose alteration compromises germ cell immortality. I

NIAID Data Ecosystem70

Epigenetic and chromatin profiling of wild-type and Dnmt3a-deficient B1 and B2 B cells. (CUT&RUN)

细胞表观遗传调控

B细胞发育分子机制

We have comprehensively interrogated wild type B1 and B2 B lineage cells and their progenitors. In mice bearing a conditional deletion of Dnmt3a in the B lineage, we integrated a variety of whole-geno

NIAID Data Ecosystem70

AMPK regulates germline stem cell quiescence and integrity through an endogenous small RNA pathway

干细胞应激响应

细胞表观遗传调控

During suboptimal growth conditions, Caenorhabditis elegans larvae undergo a global developmental arrest called “dauer.” During this stage, the germline stem cells (GSCs) become quiescent in an AMP-ac

Figshare2019-06-05 更新50

BRPF1 co-occupies with H3K4me3 and H3K23ac in human ESCs essential to pluripotency [ATAC-seq]

细胞表观遗传调控

组蛋白修饰互作

Post-translational modifications (PTMs) on histones play essential roles in cell fate decisions during development. However, how these PTMs are recognized and coordinated remains to be fully illuminat

NIAID Data Ecosystem70

Complete RIP-seq g:Profiler results.

RNA-蛋白质互作组学

细胞表观遗传调控

DND1 is essential to maintain germ cell identity. Loss of Dnd1 function results in germ cell differentiation to teratomas in some inbred strains of mice or to somatic fates in zebrafish. Using our kno

Figshare2023-03-01 更新60

Regulation of pluripotency and self-renewal of ES cells through epigenetic-threshold modulation and mRNA pruning

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