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Crystal structure of MMP12 in complex with hydroxamate inhibitor LP168.

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of MMP12 in complex with hydroxamate inhibitor LP168. Descriptor: 2-[2-[4-(4-methoxyphenyl)phenyl]sulfonylphenyl]-~{N}-oxidanyl-ethanamide, CALCIUM ION, Macrophage metalloelastase, ... Authors: Vera, L, Nuti, E, Rossello, A, Stura, E.A. Deposit date: 2017-10-05 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies. J. Med. Chem., 61, 2018
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2017-10-05
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