X-ray co-crystal structure aminobenzimidazole triazine 1 bound to Lck
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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X-ray co-crystal structure aminobenzimidazole triazine 1 bound to Lck Descriptor: N-phenyl-1-{4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl}-1H-benzimidazol-2-amine, Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION Authors: Huang, X. Deposit date: 2008-01-16 Release date: 2008-09-16 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity. J.Med.Chem., 51, 2008
创建时间：
2008-01-16
