Gene clusters syntenic with non mycobacterial organisms and not observed in other mycobacteria(a).

(a)Clusters comprising ��3 syntenic genes.(b)The organism and the homolog of the 5�� M. abscessus gene product (in brackets, entry name in Swiss-Prot/TrEMBL database) are indicated.(c)Upstream, MAB_0292c is homologous to an ISX08 transposase from Saccharopolyspora erythraea.(d)Also A6UZN8_PSEA7-A6UZN6_PSEA7 from Pseudomonas aeruginosa (strain PA7) (see also Fig. 3).(e)Partial synteny (MAB_0888c-0890c) in B. cepacia.(f)Downstream, MAB_0920 is homologous to a phenylacetic acid-responsive trancriptional repressor gene from Kineococcus radiotolerans.(g)Also Q0SCR6_RHOSR�CQ0SCS7_RHOSR from Rhodococcus sp. (strain RHA1).(h)Partial synteny (MAB_0906-0910) in B. cepacia.(i)Also A5G4D2_GEOUR- A5G4D6_GEOUR from Geobacter uraniireducens (strain Rf4) (see also Fig. 3)(j)Also syntenic regions in B. cepacia and in the pathogens Salmonella Paratyphi A, Salmonella Typhimurium, Salmonella Typhi, and Burkholderia mallei.(k)Just upstream, MAB_2254c is homologous to a PPE protein from Mycobacterium vanbaalenii.(l)This cluster has only two genes but is part of a composite region encoding various polyketide synthases (see upstream, MAB_2255-MAB_2257).(m)Just downstream, MAB_2259 is homologous to a putative O-methyltransferase gene from Myxococcus xanthus.(n)MAB_2284 (homologous to Q9K3G5) is also homologous to the protein PrnC gene from Burkholderia cepacia.(o)Except MAB_3570c, which is homologous to a 4��-phosphopantetheinyl transferase gene from the Actinomycetales (A3R4S1_9ACTO).(p)MAB_3574c is also homologous to a 3-oxoacyl-[acyl-carrier-protein] synthase III from Frankia alni.(q)Partial synteny (MAB_3621c-MAB_3622c) in B. cepacia.Abbreviations: Mabs, M. abscessus; CDS, coding sequence.