Expression data from PrimeView human gene expression array

Gene expression in A498 cells infected with shCtrl and shMCM8 was detected with a PrimeView human gene expression array. We performed Affymetrix Human Gene Chip Prime View analysis on shCtrl and shMCM8 A498 cells. Of the 2415 differentially expressed genes (DEGs) found in shMCM8 and shCtrl A498 cells, 1263 were up-regulated and 1152 were down-regulated based on the threshold of absolute fold change ≥ 2 and FDR < 0.05 The total RNA of A498 cells infected with shCtrl and A498 was extracted. The RNA sequencing was performed with Affymetrix human GeneChip PrimeView and the outcomes were scanned by Affymetrix Scanner 3000. The statistical significance of raw data was completed by a Welch t-test with Benjamini-Hochberg FDR (|Fold Change| ≥ 2 and FDR < 0.05 as significant).