Gene expression for several new potential therapeutic targets to improve post-stroke recovery in aged animals.

Legend↔ no changes vs contralateral side.↑ upregulated vs contralateral side.↓ downregulated vs contralateral side.y/3d Young, 3d post-stroke.y/14d Young, 14d post-stroke.A/3d Aged, 3d post-stroke.A/14d Aged, 14d post-stroke.Confirmation of arrays data for new stroke-related genes was done by RT-PCR. Modulation of gene/protein activity by the indicated drugs may, in combination or alone, improve post-stroke recovery in aged animals. For most of the upregulated genes there is a therapeutic option but not for downregulated genes.