Effect of depletion of YAP1 on gene expression in triple negative breast cancer. Effect of depletion of YAP1 on gene expression in triple negative breast cancer

To investigate the cooperative function HJURP/YAP1/NDRG1 in the regulation of progression in triple negative breast cancer, we established MDA-MB-231 cell lines in which each target gene has been knocked down by shRNA. We then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for MDA-MB-231 cells and its KD derivatives (shYAP1).