Discovery of ASTX029, a clinical candidate which modulates the phosphorylation and catalytic activity of ERK1/2
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Discovery of ASTX029, a clinical candidate which modulates the phosphorylation and catalytic activity of ERK1/2 Descriptor: 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)ethyl]-3~{H}-isoindol-1-one, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... Authors: O'Reilly, M. Deposit date: 2021-03-02 Release date: 2021-10-06 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.775 Å) Cite: Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J.Med.Chem., 64, 2021
创建时间：
2021-03-02
