Top2b

ENCODES a protein that exhibits chromatin binding (ortholog); ribonucleoprotein complex binding (ortholog); INVOLVED IN axonogenesis (ortholog); B cell differentiation (ortholog); cellular response to ATP (ortholog); PARTICIPATES IN doxorubicin pharmacodynamics pathway; doxorubicin response pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); B-Cell Immunodeficiency, Distal Limb Anomalies, and Urogenital Malformations (ortholog); congenital disorder of deglycosylation (ortholog); FOUND IN chromosome (ortholog); cytosol (ortholog); heterochromatin (ortholog)

编码一种展现染色质结合（同源）；核糖核蛋白复合物结合（同源）；参与轴突发生（同源）；B细胞分化（同源）；细胞对ATP的反应（同源）；参与阿霉素药代动力学途径；阿霉素反应途径；依托泊苷药代动力学途径；与自闭症谱系障碍（同源）相关；B细胞免疫缺陷、远端肢体畸形和泌尿生殖系统畸形（同源）；先天性去糖基化障碍（同源）；存在于染色体（同源）；细胞质（同源）；异染色质（同源）