Circadian parameters of activity in LD and DD in WT, Q175 Het and Hom mice from 3 months to 12 months of age.

Parameters were analyzed using one-way ANOVA, and the F and P statistics are reported for genotype comparisons within each age group. H values are reported from ANOVA on ranks comparisons in the event of failed normality or equal variance tests. * indicates that post hoc Bonferroni’s t-tests detected significant differences compared to WT, and ∧ indicates significant differences were detected between Het and Hom groups.