Raw data for: Crosstalk between regulatory elements in the disordered TRPV4 N-terminus modulates lipid-dependent channel activity
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https://zenodo.org/record/7457013
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资源简介：
This repository contains raw data and code related to "Crosstalk between regulatory elements in the disordered TRPV4 N-terminus modulates lipid-dependent channel activity" by Goretzki et al.
Included are molecular dynamics parameter files, initial structures after system equilibration, production trajectories, and final structures of simulations of:
1. coarse-grained IDRs on membrane, and force and position data for restrained c-termini. Trajectories are subsampled with one frame every 50 ns.
2. The tetrameric TRPV4 core in a POPC in atomistic resolution. Trajectories are sampled with one frame every 1 ns.
3. The isolated ARD in solution in atomistic resolution. Trajectories are subsampled with one frame every 1 ns.
Contact information:
Name: Stefan L. Schaefer
Institution: Department of Theoretical Biophysics, Max Planck Institute of Biophysics
Address: Max-von-Laue-Str. 3, 60438 Frankfurt am Main, Germany
Email: stefan.schaefer@biophys.mpg.de
Name: Ainara Claveras Cabezudo
Institution: Department of Theoretical Biophysics, Max Planck Institute of Biophysics
Address: Max-von-Laue-Str. 3, 60438 Frankfurt am Main, Germany
Email: ainara.claveras@biophys.mpg.de
创建时间：
2023-05-25
