Effect of progerin on p53-deficient vascular smooth muscle cells. Homo sapiens
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA206061
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资源简介：
Analysis of p53-deficient (E6-expressing) human vascular smooth muscle cells (VSMCs) that express progerin, a mutated form of lamin A resposible for Hutchinson- Gilford progeria syndrome (HGPS). p53 pathway is associated with HGPS. Results provide insight into molecular mechanisms underlying vascular dysfunction of HGPS caused by other than p53 pathway. Overall design: The gene expression of VSMCs induced to express E6 and either lamin A or progerin by retroviral vectors.
创建时间：
2013-05-31
