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In vitro characterization of P. berghei blood stages (IC50 data) [nM]

NIAID Data Ecosystem2026-03-07 收录

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https://figshare.com/articles/dataset/_In_vitro_characterization_of_P_berghei_blood_stages_IC_50_data_nM_/598498 数据链接链接失效反馈

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In vitro characterization of P. berghei blood stages (IC50 data) [nM]

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创建时间：

2013-02-21

疟疾抗药性

抗疟药物筛选

Lines of Plasmodium falciparum malaria parasites were selected for resistance to candidate antimalarial compounds in vitro and sequenced to determine mutational changes associated with resistance.

NIAID Data Ecosystem90

Photocatalytic Unsymmetrical Coupling of 2‑Substituted Quinolines: Synthesis and Evaluation of the Antiplasmodial Potential of β‑Norbenzomorphan Frameworks

有机合成光催化

抗疟药物筛选

We herein report unsymmetrical coupling of 2-methylquinolines under the blue LED light conditions using iridium-based photocatalyst. This methodology represents the direct synthetic method for the β-n

Figshare2020-07-24 更新30

Antimalarial Activities of Aminooxy Compounds

抗疟药物筛选

化合物效力评估

Twenty-three aminooxy compounds have been examined for their ability to inhibit the growth of the malaria parasite Plasmodium falciparum in vitro. Eight of these compounds were found to have 50% inhib

PubMed Central10

Table_2_Generation of Novel Plasmodium falciparum NF135 and NF54 Lines Expressing Fluorescent Reporter Proteins Under the Control of Strong and Constitutive Promoters.xlsx

疟原虫转基因报告株系

抗疟药物筛选

Transgenic reporter lines of malaria parasites that express fluorescent or luminescent proteins are valuable tools for drug and vaccine screening assays as well as to interrogate parasite gene functio

NIAID Data Ecosystem40

The effect of PDE inhibitors on particulate fractions isolated from P. falciparum parasites.

抗疟药物筛选

酶抑制剂药理学

IC50 values (the concentration of compound that gave 50% inhibition of native PDE activity) are mean ± SEM in μM and were calculated using the Prism software package (GraphPad Software, Inc.). Percent

Figshare2015-12-03 更新30

<i>In vitro</i> characterization of <i>P. berghei</i> blood stages (IC<sub>50</sub> data) [nM]

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