Expression Atlas

The Expression Atlas is a free resource providing information on gene expression patterns under different biological conditions in a variety of species. Gene expression data is re-analysed in-house to detect genes showing interesting baseline and differential expression patterns, allowing a user to ask questions such as "what are the genes expressed in normal human liver" and "what genes are differentially expressed between water-stressed rice plants and controls with normal watering?" The resource features proteomics data sets provided by collaborators for corroboration between gene- and protein-level expression results. The latest component, Single Cell Expression Atlas, systematically reanalyses and visualises single cell RNA-sequencing datasets and helps answer questions such as what cell population a gene can act as a marker gene.基因表达图谱（Expression Atlas）是一款免费资源，可提供多种物种在不同生物学条件下的基因表达模式相关信息。本团队通过内部渠道对基因表达数据进行重新分析，以筛选出具备研究价值的基础表达与差异表达模式基因，从而支持用户提出诸如“正常人类肝脏中表达的基因有哪些”以及“水分胁迫水稻植株与正常浇水对照组间存在差异表达的基因有哪些”等科研问题。本资源还收录了合作方提供的蛋白质组数据集，用于佐证基因与蛋白质两个层面的表达结果。其最新组成模块——单细胞基因表达图谱（Single Cell Expression Atlas），可系统性地对单细胞RNA测序数据集开展重新分析与可视化工作，并助力解答“某基因可作为何种细胞群的标记基因”等相关问题。

搜集汇总

背景与挑战

背景概述

Expression Atlas是一个免费资源，提供多种物种在不同生物条件下的基因表达模式信息。它通过内部重新分析基因表达数据，识别具有显著基线或差异表达的基因，并包含单细胞RNA测序数据集的分析与可视化功能。