Data for: The role of insulin-like growth factor 1 in ALS cell and mouse models: a mitochondrial protector
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all the experiments were repeated at least 3 times.
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2018-11-16
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Additional file 2 of Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALS
Additional file 2: Table S1. Integrated analysis of RNA-sequencing and H3K4me2 ChIP-sequencing to identify spermidine-modulated gene signatures in ALS (G93A).
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A low level of expression of C-terminally truncated human FUS causes extensive changes in the spinal cord transcriptome of asymptomatic transgenic mice
A number of mutations in a gene encoding RNA-binding protein FUS was linked to the development of a familial form of amyotrophic lateral sclerosis known a FUS-ALS. C-terminal truncations of FUS by a n
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Neuromuscular Junction Innervation and Motor Function Are Preserved by Restoring Muscarinic Signaling in Perisynaptic Glia in ALS, Tremblay et al. - Figure 8 - GFAP and Iba1
Raw data and analysis file for Figure 8 - Panel c, d and e (GFAP and Iba1) and Figure S1
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ALS-Associated KIF5A Mutations Abolish Autoinhibition Resulting in a Toxic Gain of Function [RNA-seq]
Purpose: The goal of this study was to identify gene expression changes in iMNs containing a patient KIF5a mutation compared to an isogenic control. Further, splicing changes were evaluated in the mu
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