Summary of survival ratios, rupture times and involved residues of hydrogen bonds and salt bridges obtained from free and steered simulations.

*ECC is an abbreviation of equilibrated complex conformation. Letter H and S expresses the two types of bonds, such as hydrogen bond and salt bridge, respectively. The heading I and II denote two different ECCs of of 6B4 bound to GPIbα, the superscript numbers on residues (Column 5 and 3) designate the positions of their respective involved residues in sequences of 6B4 and GPIbα with serial numbering, and, the donor- and acceptor-atoms (Column 6) on paratope residues (Column 5) together with their respectively partners (Column 4) on epitope residues (column 3) contribute to bonds in binding site. All bonds, which were derived from static analyses and/or from thrice independent free and steered MD simulations with equilibrated conformation I and II, respectively, were designated by the symbol “+” and/or nonzero values (mean ± SD) of survival ratios and rupture times of bonds.