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Active enhancer landscape during spermatogenesis.

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NIAID Data Ecosystem2026-04-29 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP194663
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资源简介:
Active enhancers are identified by H3K27ac ChIP-seq analysis. To determine the dynamics of active enhancers during spermatogenesis, we performed H3K27ac ChIP-seq and detected reagions of active enhancers during spermatogenesis. We analyzed four representative stages of spermatogenesis: Thy1+ undifferentiated spermatogonia, which contains spermatogonial stem cells and progenitor cells; c-Kit+ differentiating spermatogonia from P7 testes; purified pachytene spermatocytes (PS) undergoing meiosis; and postmeiotic round spermatids (RS) from adult testes. Overall design: ChIP-seq analyses using wild-type and Scml2-KO spermatogenic cells
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2021-07-09
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