Campylobacter jejuni subsp. jejuni str. RM3439 Genome Sequencing

The food-borne pathogens Campylobacter jejuni (Cj) and C. coli (Cc) produce capsular polysaccharides (CPS) that are the major antigenic determinants of the classical Penner serotyping system that distinguishes these Campylobacters into 65 groups. In order to examine the genomic diversity of Cj and Cc, and to identify DNA signatures for the development of faster and cheaper typing assays, we have determined the draft genome sequences of 38 Cj and 18 Cc strains representing 56 different Penner serotypes.

食源性病原体空肠弯曲菌（C. jejuni，Cj）和大肠弯曲菌（C. coli，Cc）能产生荚膜多糖（CPS），这些多糖是经典Penner血清分型系统的主要抗原决定因素，该系统将弯曲菌区分成65个不同的血清群。为了研究Cj和Cc的基因组多样性，并鉴定用于开发更快、更经济的分型检测方法的DNA特征，我们已确定了38个Cj和18个Cc菌株的草图基因组序列，这些菌株代表56种不同的Penner血清型。