Angiogenesis

This pathway is a concise and simplified version of the basic proteins involved in angiogenesis. The proces is regulated by hyopoxia, which results in the transcription of eg. VEGF1, FGF2, PDGFbeta, MMP9, MMP2 and Ang1. These proteins bind to their receptors and by doing this they initiate different pathways that result in vessel formation.

本途径为参与血管生成的基本蛋白质的简洁化简述。该过程受缺氧调节，进而导致例如VEGF1、FGF2、PDGFbeta、MMP9、MMP2和Ang1等蛋白的转录。这些蛋白质与其受体结合，通过此过程启动多种途径，最终导致血管的形成。